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Addressing clinical limitations of glutaminase inhibitors: novel strategies for osimertinib-resistant lung cancer by exploiting glutamine metabolic dependency

Viability was estimated using CellTiter-Glo luminescence reagent (CTG, Promega)

These findings demonstrated that without the twenty day recovery allowed occurring with IH EARLY , the IH 10 suppresses the Tbr2 + cell population and thus, suggests that IH initializes two seemingly opposing processes on adult neurogenesis prior to transitioning from the first critical period